2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-131280R
    Devaleryl Valsartan Impurity (Standard)
    L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM.
    Devaleryl Valsartan Impurity (Standard)
  • HY-W017434R
    3,4-Dimethylbenzoic acid (Standard)
    3,4-Dimethylbenzoic acid (Standard)
  • HY-131306
    Δ2-cis-Hexadecenoic acid
    Δ2-cis-Hexadecenoic acid is an unsaturated fatty acid that is a hydrolysate of lipopolysaccharide (HY-D1056).
    Δ2-cis-Hexadecenoic acid
  • HY-12753S
    Debutyldronedarone-d7
    		≥98.0%
    Debutyldronedarone-d7 is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone (HY-A0016) in humans.Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent[1][2].
    Debutyldronedarone-d<sub>7</sub>
  • HY-78841
    (2S,4S)-Sacubitril
    (2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is a potent NEP inhibitor that can be used for the research of heart failure.
    (2S,4S)-Sacubitril
  • HY-W006000R
    Tetrachlorocatechol (Standard)
    Tetrachlorocatechol (Standard)
  • HY-133695
    Florfenicol amine
    Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases.
    Florfenicol amine
  • HY-143965S
    Imidacloprid impurity 2-d4 hydrochloride
    Imidacloprid impurity 2-d4 (hydrochloride) is the deuterium labeled Imidacloprid impurity 2-d4 (hydrochloride)[1].
    Imidacloprid impurity 2-d<sub>4</sub> hydrochloride
  • HY-116026R
    3-Hydroxycarbofuran (Standard)
    3-Hydroxycarbofuran (Standard) is the analytical standard of 3-Hydroxycarbofuran. This product is intended for research and analytical applications. 3-Hydroxycarbofuran, a major metabolite of Carbofuran, is a reversible acetylcholinesterase (AChE) inhibitor.
    3-Hydroxycarbofuran (Standard)
  • HY-135325R
    4-Hydroxyacetophenone oxime (Standard)
    Pyrrole-2-carboxaldehyde (Standard) is the analytical standard of Pyrrole-2-carboxaldehyde. This product is intended for research and analytical applications. Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase.
    4-Hydroxyacetophenone oxime (Standard)
  • HY-W013186S1
    Lansoprazole sulfide-13C6
    Lansoprazole sulfide-13C6 is a deuterated labeled Lansoprazole sulfide.
    Lansoprazole sulfide-<sup>13</sup>C<sub>6</sub>
  • HY-113322
    3-Hydroxyquinine
    3-Hydroxyquinine is a metabolite of Quinidine (HY-B1751). 3-Hydroxyquinine prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in an isolated rat heart reperfusion arrhythmia model in a concentration-dependent manner. 3-Hydroxyquinine can be used in the study of cardiac arrhythmias.
    3-Hydroxyquinine
  • HY-G0017R
    N-Desmethyl imatinib (Standard)
    Clobutinol (hydrochloride) (Standard) is the analytical standard of Clobutinol (hydrochloride). This product is intended for research and analytical applications. Clobutinol hydrochloride is a compound that has anti-tussive effects. Clobutinol hydrochloride affects heart rate and blood pressure, it can be used for cough related research.
    N-Desmethyl imatinib (Standard)
  • HY-W338852R
    Gentisuric acid (Standard)
    Gentisuric acid (Standard)
  • HY-23093R
    L-Aspartyl-L-phenylalanine (Standard)
    L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM.
    L-Aspartyl-L-phenylalanine (Standard)
  • HY-135375
    O-Methyl Atorvastatin calcium
    O-Methyl Atorvastatin (hemicalcium) is an impurity of Atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids.
    O-Methyl Atorvastatin calcium
  • HY-116016AR
    Etilevodopa (hydrochloride) (Standard)
    Etilevodopa (hydrochloride) (Standard)
  • HY-W144308R
    Tetrachlorohydroquinone (Standard)
    Glycerol Monoleate (Standard) is the analytical standard of Glycerol Monoleate. This product is intended for research and analytical applications. Glycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro.
    Tetrachlorohydroquinone (Standard)
  • HY-131275
    Imatinib Impurity E
    Imatinib Impurity E is the impurity of Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV.
    Imatinib Impurity E
  • HY-G0007S
    Omeprazole sulfone-d3
    Omeprazole metabolite Omeprazole sulfone-d3 is the deuterium labeled Omeprazole metabolite Omeprazole sulfone. Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor.
    Omeprazole sulfone-d<sub>3</sub>
Cat. No. Product Name / Synonyms Application Reactivity